Investigator Initiated Study: Metabolic Disease
Investigator-Initiated Studies (IIS)
In general, IIS are not registrational studies, and they may be proof of concept or exploratory in nature. The budget for these studies should reflect fair market value for all costs and cannot include direct salary support for the principal investigator.
Boehringer Ingelheim may provide financial support and/or drugs for an approved IIS. BI does not serve as the regulatory sponsor for IIS. Investigators are required to apply for support via an online application process.
Although the research interests listed within the following therapeutic areas are of focus to BI, other research interests may be considered.
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- Describe the current care pathway, referral patterns and gaps in effective screening, diagnosis, and treatment of Obesity and/or MASH/MASLD; and the role of Health Care Providers (HCPs) in appropriate and timely diagnosis and treatment of Obesity and/or MASH/MASLD
- Define the drivers and approach of HCPs in diagnosing and treating patients with Obesity and/or MASH/MASLD (e.g., time to diagnosis and treatment, patient characteristics)
- Understand patient expectations and factors influencing a patient’s acceptance of treatment; and approaches to encourage and support medication adherence and persistence for treatment of Obesity and/or MASH/MASLD
- Explore the role of Glucagon and GLP-1 receptors in metabolic health (e.g., distribution, activation). Explore body metabolism and energy expenditure
- Describe the physical and psychological burden of disease for patients living with Obesity and/or MASH/MASLD and how stigma and bias can impact clinical management
- Explore additional opportunities to characterize the positive impact of pharmacologic treatments on quality of life (non-scale victories) for patients living with Obesity and/or MASH/MASLD
- Explore the interconnectivity of CRM diseases including obesity, CKD, MASH/MASLD
Documents
Proposals in the following areas are not being considered
Biosimilars and Fibrosing ILDs
PIRA™ suggested Proposal
PIRA™ proposals are AI generated and are not reviewed or endorsed by the sponsoring company.